FIP Treatment FAQs – GS-441524 Questions Answered

Perguntas frequentes

O QUE VOCÊ DEVE SABER SOBRE O TRATAMENTO DA PIF

O tempo de tratamento recomendado é de 12 semanas. No entanto, a duração real do tratamento pode depender de muitos fatores, como a rapidez com que seu gato responde ao tratamento, o estágio da infecção por PIF no momento do início do tratamento e sua situação financeira pessoal.

Sim, o GS é um tratamento antiviral e pode ser usado com outros medicamentos para melhorar a saúde geral do seu gato. No entanto, o uso de lisina não é recomendado em conjunto com o GS.

Peixe fresco cozido e outros alimentos naturais. Se o seu gato estiver com diarreia, considere mudar para ração seca por alguns dias, até que a diarreia cesse.

À medida que seu gato começa a se recuperar, ele ganhará peso conforme seu apetite retorna e ele volta a se alimentar normalmente. Pese seu gato uma vez por semana e ajuste a dosagem da medicação de acordo. Mantenha contato frequente com seu veterinário para que quaisquer complicações potenciais, como danos ao fígado e aos rins ou infecções, possam ser tratadas.

Early symptoms common to both wet and dry FIP include persistent fever that does not respond to antibiotics, unexplained weight loss, loss of appetite, lethargy, and dull coat condition.

In wet FIP, additional signs include a visibly swollen or distended abdomen, laboured breathing (if fluid accumulates in the chest), and general weakness. In dry FIP, symptoms vary widely depending on which organs are affected — these can include neurological signs such as wobbling, tremors, or seizures; eye changes such as cloudiness, uneven pupil size, or inflammation; jaundice; or unexplained changes in behaviour.

If your cat is displaying any combination of these signs — particularly persistent fever alongside weight loss and lethargy — contact your veterinarian promptly. Early diagnosis significantly improves treatment outcomes.

FIP presents in two primary forms. Wet (effusive) FIP is characterised by fluid accumulation in the abdomen or chest cavity, and tends to progress rapidly. Dry (non-effusive) FIP involves inflammatory lesions in organs without significant fluid build-up, and typically progresses more slowly.

Both forms are treated with GS-441524 using the same core protocol. What changes is the starting dose and urgency of treatment. Neurological and ocular FIP — which can occur in either form — require higher doses and must be treated with injections only. If you are unsure which form your cat has, share your cat's diagnosis and bloodwork with our treatment team and we will advise on the correct protocol.

FIP develops when the feline enteric coronavirus (FCoV) — a common intestinal virus that most cats carry without ever falling ill — undergoes a mutation inside the cat's body. This mutation transforms it into the feline infectious peritonitis virus (FIPV), which triggers a severe immune response and attacks the cat's own tissues.

FCoV itself is contagious and spreads between cats through shared litter boxes, food and water bowls, and close contact — particularly in multi-cat households, shelters, and catteries. However, FIP itself does not spread directly from cat to cat. The mutation that causes FIP occurs randomly and cannot be predicted. Young cats under two years old, males, and purebred cats are at statistically higher risk of developing FIP after FCoV exposure.

This is one of the most common and understandably confusing questions from cat owners. FIP can develop in indoor cats because the feline coronavirus (FCoV) that causes it is extremely widespread — many cats are exposed in early life, particularly if they came from a breeder, cattery, shelter, or multi-cat household before joining your home.

FCoV can remain dormant in a cat's body for months or years before the random mutation event that triggers FIP. An indoor cat that has had no outside contact in years can still develop FIP from a coronavirus exposure that happened much earlier in its life. It is not a sign that anything went wrong in your care — the mutation is unpredictable and not preventable once FCoV exposure has occurred.

FIP itself is not directly transmitted between cats. What spreads between cats is the underlying feline coronavirus (FCoV), which in most cases causes no symptoms at all. The mutation that transforms FCoV into FIP occurs spontaneously inside an individual cat's body and cannot be passed on.

FCoV is shed in faeces and spreads through shared litter boxes, grooming, and close contact. Managing hygiene in multi-cat environments — particularly litter box cleanliness — is the primary way to limit FCoV circulation and reduce the overall risk of any individual cat developing FIP.

FIP itself is not directly contagious between cats. However, the underlying feline coronavirus (FCoV) that mutates into FIP is contagious and is commonly spread through shared litter boxes, food bowls, and close contact.

Most cats that carry FCoV never develop FIP — only a small percentage experience the viral mutation that causes the disease. During your cat's FIP treatment, standard hygiene precautions are sufficient: keep litter boxes clean, wash food and water bowls regularly, and monitor other cats in the household for any changes in behaviour, appetite, or weight. If another cat in your home develops symptoms, contact us promptly.

There is no single definitive test for FIP. Diagnosis typically involves a combination of approaches:

Blood tests are usually the starting point — looking at the albumin-to-globulin (A/G) ratio, white blood cell count, protein levels, and inflammatory markers. A low A/G ratio combined with clinical signs strongly suggests FIP. The Rivalta test can be performed on fluid from effusive cases and has high specificity for FIP. Immunofluorescence testing on fluid or tissue samples can detect the FIPV antigen directly. Advanced tools such as AGP testing and FIPV RT-PCR on effusion fluid provide greater certainty. In unclear cases, biopsy of affected tissue remains the most definitive method of confirmation.

If you suspect FIP, work with your veterinarian to build a diagnostic picture — no single result rules it in or out on its own.

There is currently no guaranteed method to prevent FIP, as the mutation from feline coronavirus to FIPV occurs unpredictably. However, the following measures reduce the risk of FCoV exposure and transmission:

Keep litter boxes clean and disinfect them regularly. Avoid overcrowding — FCoV spreads more readily in high-density cat environments such as shelters and multi-cat households. When introducing a new cat, isolate them initially and have them tested for FCoV before mixing with resident cats. Reducing environmental stressors, which are known to increase viral susceptibility, also plays a supporting role. A FIP vaccine exists in some markets but has shown limited effectiveness in clinical practice and is not widely recommended.

Without treatment, the prognosis for FIP is extremely poor. Wet FIP progresses rapidly — most untreated cats survive only days to a few weeks after symptoms appear. Dry FIP progresses more slowly, but remains fatal without antiviral intervention. The median survival time from diagnosis without treatment is approximately 9 days.

With GS-441524 treatment, the outlook has changed dramatically. The majority of cats that complete the full 84-day protocol reach sustained remission and go on to live normal, healthy lives. Treatment should begin as early as possible — delay reduces the likelihood of a full response, particularly in advanced or neurological cases. Contact our treatment team immediately if your cat has been diagnosed or you suspect FIP.

Yes. The majority of cats that complete a full course of GS-441524 treatment go on to live normal, healthy lives. In clinical studies, most cats in sustained remission after the 84-day protocol show no long-term health consequences from the infection itself.

Some cats experience residual effects from organ involvement during the active disease phase — particularly in cases with neurological or ocular complications — but these typically resolve or stabilise after treatment ends. Weight regained during treatment is usually maintained. Most owners report that their cats return fully to pre-FIP behaviour within weeks of completing the protocol.

Completing the 84-day protocol is the end of active treatment, not the end of monitoring. After your cat finishes the course, a 12-week observation period begins. During this period, your cat should not be on any antiviral medication. If no signs of FIP return during those 12 weeks — no fever, no weight loss, no fluid accumulation, and no changes in behaviour — your cat is considered in sustained remission.

Bloodwork at the end of treatment and again at the end of the observation period will confirm remission. Do not stop treatment early based on clinical appearance alone — many cats look healthy before the virus is fully suppressed. Stopping short increases the risk of relapse.

The total cost of treatment depends on your cat's weight, the FIP type, and whether you use injectables or oral capsules. For a standard 84-day course, most owners should budget for 3 monthly packs of capsules or the equivalent in injectable vials, adjusted for their cat's weight bracket.

We recommend ordering all 3 packs at the start of treatment to avoid any supply interruption mid-course. If cost is a concern, contact our treatment team — we can discuss the most efficient treatment configuration for your cat's weight and condition. We also encourage owners with unused medication after a completed treatment to donate it to families who cannot afford a full course.

The earliest signs of FIP are often non-specific and easy to overlook. Persistent fever that does not respond to antibiotics is typically the first indicator. This is usually accompanied by loss of appetite, unexplained weight loss, lethargy, and a dull or unkempt coat. Some cats also develop mild digestive upset in the early stages.

As the disease progresses, more specific signs emerge depending on the form. In wet FIP, a visibly swollen or distended abdomen develops as fluid accumulates. In dry FIP, signs vary more widely and may include neurological changes such as loss of coordination, tremors, or seizures, as well as eye abnormalities like cloudiness or uneven pupil size. If your cat is showing any combination of these early signs — especially persistent fever alongside weight loss — contact your veterinarian immediately. Early diagnosis and prompt treatment significantly improve outcomes.

Yes — with treatment. FIP was once considered almost universally fatal, and without antiviral intervention it still carries an extremely poor prognosis. The median survival time without treatment is approximately 9 days from the point of diagnosis.

With GS-441524 antiviral treatment, the outcome has changed fundamentally. Across multiple independent clinical studies covering over 650 cats, the combined treatment success rate is approximately 92%. The majority of cats that complete the full 84-day protocol reach sustained remission and go on to live normal, healthy lives. The key factors that determine survival are starting treatment as early as possible, dosing correctly by body weight throughout the protocol, and completing the full 84 days without interruption. If your cat has been diagnosed with FIP, contact our treatment team immediately — time is the most critical variable.

WHAT YOU SHOULD KNOW ABOUT FIP TREATMENTS

The standard treatment course is 84 days (12 weeks). Most cats complete the full protocol and achieve remission within this period.

In practice, treatment duration can vary. Cats that begin treatment in the early stages of FIP typically respond faster. Those with advanced disease, neurological involvement, or ocular complications may require an extended course beyond 84 days. Your cat's bloodwork and clinical response at regular checkpoints will guide any adjustments.

GS-441524 is an antiviral and is generally compatible with other medications used to support your cat's overall health during treatment.

One exception: lysine is not recommended alongside GS-441524. Research has shown that lysine supplementation does not benefit cats with viral infections and may interfere with treatment. If your cat is currently taking lysine, discontinue it before starting the FIP treatment protocol.

If you are unsure whether a specific medication or supplement is compatible with GS-441524, contact our treatment team before combining.

Nutrition plays an important supporting role during treatment. High-quality protein helps maintain body weight and supports immune function — cooked fresh fish, chicken, or other natural whole foods are good options and are generally well tolerated.

Appetite loss is common in FIP cats, particularly in the early weeks of treatment. If your cat is reluctant to eat, warming the food slightly or offering smaller, more frequent meals can help stimulate interest.

If your cat develops diarrhea during treatment, temporarily switching to a dry food diet for a few days can help firm the stool. If diarrhea persists beyond 48 hours or is accompanied by lethargy or vomiting, contact our treatment team — it may indicate a dosing or absorption issue that needs attention.

Avoid raw fish during treatment. Raw fish contains thiaminase, an enzyme that breaks down thiamine (Vitamin B1), which can cause neurological complications in cats already under systemic stress.

As treatment takes effect, you will typically see your cat's appetite return and body weight increase — both are positive signs of recovery. Weigh your cat once a week throughout the treatment course and adjust the dosage accordingly, as GS-441524 and E

TRATAMENTO POR INJEÇÃO

As concentrações mais elevadas são mais adequadas para gatos de maior porte e/ou para aqueles que sofrem de sintomas mais graves de PIF (Peritonite Infecciosa Felina).

Uma injeção por dia, com base no peso corporal do seu gato, durante 12 semanas.

Para calcular a dosagem, utilize nossa calculadora de dosagem. Não recomendamos reduzir a dosagem durante o tratamento, pois isso pode aumentar a resistência viral ao medicamento GS.

Assista ao nosso vídeo instrutivo para obter instruções passo a passo sobre como realizar injeções subcutâneas em casa.

TRATAMENTO ORAL

Para melhores resultados, utilize as cápsulas 30 dias após o tratamento injetável ou após a saúde do seu gato estar estabilizada: boa alimentação, evacuações normais e ausência de sintomas neurológicos.

Enquanto o gato continuar apresentando sintomas oculares ou neurológicos.
Enquanto o gato sofre de diarreia ou vômitos intermitentes.
Se o gato não estiver se alimentando e precisar de alimentação forçada ou administração de fluidos subcutâneos.

Administre 1 cápsula por dia. Mantenha a rotina e não pule nenhum dia de medicação. Continue o tratamento por 84 dias ou até que todos os sintomas da PIF tenham desaparecido.

Você deve mudar para uma dosagem maior, de acordo com o peso atual do seu gato. Por exemplo, se o seu gato passou de 2,4 kg para 2,8 kg, recomenda-se trocar as cápsulas rosas pelas verdes. Isso garante que seu gato esteja recebendo a quantidade suficiente dos ingredientes ativos para o tratamento.

Uma caixa contém 14 cápsulas, o suficiente para 14 dias de tratamento.

A falta de melhora ou o agravamento do quadro clínico podem ser causados por dosagem insuficiente ou má absorção pelo sistema digestivo do gato. Você deve administrar as cápsulas ao seu gato por pelo menos 5 dias antes de verificar se há alguma melhora. Após 5 dias sem melhora visível dos sintomas, você pode aumentar a dosagem de 1 para 2 cápsulas por dia ou optar por uma concentração maior. A melhor opção é recorrer às injeções, pois são o método mais confiável para administrar a dose adequada dos princípios ativos ao organismo do seu gato.

Cada gato apresenta uma taxa de absorção da cápsula diferente, com base em sua genética e fatores de saúde. A absorção exata pode ser determinada por um procedimento diagnóstico complexo e dispendioso chamado Cromatografia Líquida de Alta Eficiência (HPLC).

Cada opção de tratamento tem seus prós e contras. Ambas são eficazes para o tratamento da peritonite infecciosa felina (PIF). As injeções são precisas, mais controláveis e seus efeitos são imediatos. Recomendamos iniciar todos os tratamentos para PIF com injeções. As cápsulas orais são mais fáceis de administrar, indolores e podem ser facilmente administradas em casa. No entanto, o GS-441524 leva mais tempo para chegar à corrente sanguínea, pois precisa primeiro passar pelo sistema digestivo. Também é impossível saber quanto de GS-441524 será absorvido para combater a PIF. Recomendamos iniciar o tratamento com cápsulas somente se a condição do gato estiver estável. O vírus da peritonite infecciosa felina frequentemente danifica órgãos do sistema digestivo, como estômago, intestinos, rins e fígado, e então se espalha por todo o corpo. Órgãos danificados reduzem a função digestiva e podem levar à má absorção do GS-441524 na corrente sanguínea. Quando as cápsulas são administradas muito cedo no tratamento, isso pode prolongar o tratamento ou aumentar a probabilidade de recidivas futuras.

Você pode mudar para o tratamento injetável após iniciar o tratamento oral. No entanto, a dose inicial da injeção será de 10 mg/kg após a transição do tratamento oral para o injetável. Isso ocorre porque nossas cápsulas têm uma concentração maior do que a solução injetável. Consulte-nos sobre a dose injetável que você deseja para o seu gato.

Não recomendamos o uso de cápsulas para recidivas. Para o tratamento de recidivas, deve-se utilizar as injeções, administrando de 12 mg a 15 mg. Consulte-nos sobre a forma adequada de tratar casos de recidiva de PIF.

Sim, mas use apenas cápsulas de uma classe superior à recomendada para o peso do seu gato, e nunca de uma inferior. Lembre-se de que uma dose maior custa mais, a menos que haja uma necessidade comprovada que torne a compra de cápsulas de classe superior um desperdício de dinheiro.

Os gatos geralmente apresentam melhora dentro de 10 a 15 dias após o início do tratamento oral. Alguns gatos apresentam melhora em apenas 5 dias.

Não há efeitos colaterais conhecidos com o uso do tratamento oral. Você pode usá-lo em conjunto com outros tratamentos e suplementos recomendados pelo seu veterinário.

Para melhores resultados, o tratamento oral deve ser administrado dentro de um intervalo de 3 horas, contando a partir da última vez em que foi administrado no dia anterior. Alternativamente, pode ser administrado 1,5 horas antes ou 1,5 horas depois da administração no dia anterior.

Não aceitamos embalagens abertas ou parcialmente consumidas. Recomendamos doá-las a veterinários ou outros tutores de gatos com PIF (Peritonite Infecciosa Felina) para que possam ser usadas para ajudar a salvar gatos.

ENVIO E DESEMBARAÇO ADUANEIRO

O prazo de entrega é de 1 a 3 dias úteis para a maioria dos países asiáticos, incluindo o Oriente Médio.
O prazo de entrega é de 1 a 3 dias úteis para a Europa e principais áreas metropolitanas do Canadá, EUA e Austrália. Para a América Latina, o prazo é de 5 a 7 dias úteis. Para o México e a Colômbia, o prazo de entrega é de 1 a 3 dias úteis.

Não, não podemos enviar para todos os países devido a barreiras legais, logísticas ou alfandegárias. Entre em contato conosco caso não consiga concluir sua compra em nosso site.

SHIPPING AND CUSTOMS CLEARANCE

We ship globally. Estimated delivery times from dispatch are as follows:

Asia & GCC: 1–3 business days
Europe (including UK): 1–3 business days
USA, Canada & Australia (major cities): 1–3 business days
Mexico & Colombia: 1–3 business days
All other countries: 3–7 business days

All orders are processed and dispatched within 24 hours of payment confirmation. You will receive a tracking number by email once your order has shipped.

Time-sensitive cases: If your cat's condition is critical and you need medication urgently, contact our team via live chat before placing your order. We will do everything possible to prioritise dispatch and advise on the fastest available shipping option to your location.

We ship to the vast majority of countries worldwide. In some cases, logistical limitations or local customs regulations prevent us from delivering to specific destinations.

If your country is not available at checkout, please contact our team directly via live chat before giving up on your order. In many cases we can identify an alternative shipping route or advise on the fastest available option to reach you.

We understand that for a cat with FIP, access to treatment is urgent — we will always try to find a solution.

95% of orders are dispatched within 24 hours of payment confirmation.

The remaining 5% are dispatched within 3 business days. Delays may be caused by uncontrollable events across the regions we operate in — including national, religious, and cultural observances, natural disasters, worker protests, even geopolitical instability. We operate across multiple time zones and jurisdictions, and our local logistic partners observes a broad range of public holidays as a result.

If your cat's condition is critical and you need same-day dispatch, contact us via live chat immediately after placing your order and we will do our best to prioritise it.

Once your order has been paid, it will be scheduled for pickup with 24 hours. Once your package as been picked up, you will receive an email containing your tracking number. We ship via FedEx or DHL Express depending on your location.

You can track your shipment in real time at:

If you have not received a tracking email within 24 hours of your order confirmation, check your spam or junk folder first. If it is not there, contact our team via live chat and we will locate your shipment immediately.

If you live in North America, Oceania or Europe, GCC or Asia, your order will be fulfilled by local warehouse. As a result there is not custom clearance needed. For orders outside of these regions, about 10% of packages are randomly picked by custom for examination and clearance.

We manage our side of the process fully. Every shipment is dispatched with complete import declaration documentation, which we provide directly to the carrier — FedEx or DHL — to initiate customs clearance (when needed) on your behalf.

In most cases, your order will clear customs without any action required from you.

In some instances, your local customs authority may contact you directly to request additional documentation. If this happens, do not be alarmed — it is a routine part of international small package shipments in certain jurisdictions. Contact us immediately at info@curefip.com and we will provide everything you need to complete the clearance process promptly.

One practical note: customs processing times vary by country and are outside our control once the shipment has left our facility. If your order is time-sensitive, factor in the possibility of a short customs hold when planning your treatment start date. If you are unsure about customs requirements in your country, contact us before placing your order and we will advise.

OPÇÕES DE PAGAMENTO

Aceitamos Visa, MasterCard, PayPal e Alipay.

Você pode nos enviar uma transferência bancária. No entanto, tenha em mente que pode levar até 4 dias para recebermos os fundos e, em seguida, enviarmos o processamento PIF. Recomendamos o uso de [inserir aqui a opção de pagamento]. wise.com como uma plataforma confiável e acessível para transferências bancárias.

IMPOSTOS

Não cobramos impostos. Dependendo do seu país, você poderá ter que pagar taxas de importação. Nossas faturas são otimizadas para minimizar essas taxas.

O Google é o melhor lugar para encontrar a resposta para essa pergunta. No entanto, se você ainda tiver dúvidas, pode nos enviar uma mensagem para que possamos ajudá-lo a determinar sua possível obrigação tributária referente à compra.